Vesalius, Paracelsus and Early Modern Medicine (part 1 of 2)

A Historical View
Based on Major Changes

What were the big changes between Medieval (~500 and 1500 CE/AD) and Early Modern (~1500-1700 CE/AD) medicine in Europe?

Lecture I: Vesalius and Paracelsus

Both challenges to Galenism

Vesalius worked within the system; Paracelsus outside and against it

Andreas Vesalius (1514-1564)

Innovations in medicine and medical education:

Performed his own dissections

Comparative anatomy (animals and humans)

Relied on images to convey medical knowledge

Both revered and challenged Galen

Successfully repositioned anatomy in medical education and practice

Performed his own dissections

In medieval medicine, dissection usually done by barber-surgeons rather than University-educated physicians (see excerpt from De Fabrica in Rothman 54-60)

Dissections not illegal; restrictions on modes of acquiring and preparing cadavers

Dissection, continued

Vesalius became chair of anatomy at U of Padua in 1537 and immediately changed modes of teaching anatomy

Did own public dissections and did them regularly, supplementing with private dissections for small groups of students

Comparative Anatomy

Vesalius dissected both animal and human cadavers so that students could see their differences

This illustrated some of his major arguments with Galen, who had based his writings on animal dissections

Vesalius’s use of Images

Unlike previous scholars/teachers, relied on images to convey medical knowledge

Very few images used by other teachers of medicine, partly because of expense but also because of custom

Emphasis on visual changed medical teaching in substantial ways

Understood the difficulty of learning complex systems of the body in one lecture/dissection; supplemented with charts and later books

Did not credit his illustrators

Most likely used Jan Stephan van Calcar, Dutch artist

Emphasis on visual representations based on observation of human anatomy reflects an Early Modern intersection of medicine and art (da Vinci, for ex.) that we will continue to explore on Wednesday.

 

De Fabrica

De Humanis Corporis Fabrica
(On the Fabric of the Human Body)

Published in 1543

One of most significant books in the history of Western medicine

Systematic exploration, in separate volumes, of the bones, muscles, vascular system, nerves, abdominal and reproductive organs, and the thorax

Remarkable for the visuals as much as for its willingness to point out limitations in Galenic medicine

Vesalius’s Challenges to Galen

Like his peers, revered Galen

Like others, saw the theory and practice of medicine as an evolving process; one did not have to simply use the teachings of the ancients without bringing their own ideas and observations to bear on classic texts.

Vesalius argued that Galen didn’t have access to the right texts, that he dissected only animals, and that his followers reduced and altered his observations.

Vesalius and Galen, continued

Vesalius argued that errors in Galen reflected his use of primate subjects for dissection

His detractors argued that the human body had simply changed since Galen

Vesalius’s Arguments about Anatomy

Vesalius argued that the division of medicine from surgery created a significiant problem in the practice of healing.

Physicians lectured on principles but did not themselves explore the interior of the human body.

Conversely, barber-surgeons knew the inside of the body but could not read or explain the learned texts

Vesalius’s arguments, continued

Vesalius argued for a reunification of surgery with medicine.

Vesalius argued that anatomy was the basis of medicine and that the anatomist-lecturer must perform his own dissections.

Vesalius asserted that careful observation (empiricism) was more important than simply learning from one’s predecessors

Paracelsus (Theophrastus Philippus Aureolus Bombastus von Hohenheim) (1493-1541)

Challenged Galenic medicine as limited and not useful to actual practice

A much more substantial challenge than that posed by Vesalius, which preserved theory but questioned accuracy

Challenged academic medicine as not useful to living bodies

Contemptuous of teachings of Hippocrates and Galen and publicly burned a treatise of Avicenna

Paracelsus, continued

Attacked academic medicine and anatomy as "dead" anatomy because it did not show how the living body worked

Proposed natural philosophy based on chemical principles

Salt, sulphur, and mercury primary substances

Proposed Five "ens" or forces that governed the state of the body

Paracelsus, continued

Ens Astrale – of the heavenly bodies

Ens Veneni – of the poisons

Ens Naturale – of the natural order within the body

Ens Spirituale – of the spiritual rather than the physical

Ens Dei – of God—from whom all sickness and health proceed

Natural illnesses vs. inflictions

Emphasizes Christian basis for all his theories

Paracelsus, continued

Medical philosophies not popular in his own time; better known for prophecies and discussion of portents

In 1550-1575 had impact on European medicine

Attracted some royal patrons

Like Vesalius, indicative of decline of Galenic medicine

What did Vesalius and Paracelsus have in common?

Emphasis on observation vs. learning from classic texts

In Vesalius’s case, part of Early Modern return to original texts to recover truths and discover errors in translations

In Paracelsus’s case, rejection of academic medicine

Both valued empiricism though Paracelsus was much more radical in his stance

Questions You May Have:

Why do we distinguish the Middle Ages from the Early Modern Period?

What is the difference between "Early Modern" and "Renaissance"?

What should I try to remember about these figures in the history of medicine (Vesalius and Paracelsus)?