Vesalius, Paracelsus and Early Modern Medicine (part 1 of 2)
A Historical View
Based on Major Changes
What were the big changes between Medieval (~500 and 1500 CE/AD) and Early Modern (~1500-1700 CE/AD) medicine in Europe?
Lecture I: Vesalius and Paracelsus
Both challenges to Galenism
Vesalius worked within the system; Paracelsus outside and against it
Andreas Vesalius (1514-1564)
Innovations in medicine and medical education:
Performed his own dissections
Comparative anatomy (animals and humans)
Relied on images to convey medical knowledge
Both revered and challenged Galen
Successfully repositioned anatomy in medical education and practice
Performed his own dissections
In medieval medicine, dissection usually done by barber-surgeons rather than University-educated physicians (see excerpt from De Fabrica in Rothman 54-60)
Dissections not illegal; restrictions on modes of acquiring and preparing cadavers
Dissection, continued
Vesalius became chair of anatomy at U of Padua in 1537 and immediately changed modes of teaching anatomy
Did own public dissections and did them regularly, supplementing with private dissections for small groups of students
Comparative Anatomy
Vesalius dissected both animal and human cadavers so that students could see their differences
This illustrated some of his major arguments with Galen, who had based his writings on animal dissections
Vesalius’s use of Images
Unlike previous scholars/teachers, relied on images to convey medical knowledge
Very few images used by other teachers of medicine, partly because of expense but also because of custom
Emphasis on visual changed medical teaching in substantial ways
Understood the difficulty of learning complex systems of the body in one lecture/dissection; supplemented with charts and later books
Did not credit his illustrators
Most likely used Jan Stephan van Calcar, Dutch artist
Emphasis on visual representations based on observation of human anatomy reflects an Early Modern intersection of medicine and art (da Vinci, for ex.) that we will continue to explore on Wednesday.
De Fabrica
De Humanis Corporis Fabrica
(On the Fabric of the Human Body)
Published in 1543
One of most significant books in the history of Western medicine
Systematic exploration, in separate volumes, of the bones, muscles, vascular system, nerves, abdominal and reproductive organs, and the thorax
Remarkable for the visuals as much as for its willingness to point out limitations in Galenic medicine
Vesalius’s Challenges to Galen
Like his peers, revered Galen
Like others, saw the theory and practice of medicine as an evolving process; one did not have to simply use the teachings of the ancients without bringing their own ideas and observations to bear on classic texts.
Vesalius argued that Galen didn’t have access to the right texts, that he dissected only animals, and that his followers reduced and altered his observations.
Vesalius and Galen, continued
Vesalius argued that errors in Galen reflected his use of primate subjects for dissection
His detractors argued that the human body had simply changed since Galen
Vesalius’s Arguments about Anatomy
Vesalius argued that the division of medicine from surgery created a significiant problem in the practice of healing.
Physicians lectured on principles but did not themselves explore the interior of the human body.
Conversely, barber-surgeons knew the inside of the body but could not read or explain the learned texts
Vesalius’s arguments, continued
Vesalius argued for a reunification of surgery with medicine.
Vesalius argued that anatomy was the basis of medicine and that the anatomist-lecturer must perform his own dissections.
Vesalius asserted that careful observation (empiricism) was more important than simply learning from one’s predecessors
Paracelsus (Theophrastus Philippus Aureolus Bombastus von Hohenheim) (1493-1541)
Challenged Galenic medicine as limited and not useful to actual practice
A much more substantial challenge than that posed by Vesalius, which preserved theory but questioned accuracy
Challenged academic medicine as not useful to living bodies
Contemptuous of teachings of Hippocrates and Galen and publicly burned a treatise of Avicenna
Paracelsus, continued
Attacked academic medicine and anatomy as "dead" anatomy because it did not show how the living body worked
Proposed natural philosophy based on chemical principles
Salt, sulphur, and mercury primary substances
Proposed Five "ens" or forces that governed the state of the body
Paracelsus, continued
Ens Astrale – of the heavenly bodies
Ens Veneni – of the poisons
Ens Naturale – of the natural order within the body
Ens Spirituale – of the spiritual rather than the physical
Ens Dei – of God—from whom all sickness and health proceed
Natural illnesses vs. inflictions
Emphasizes Christian basis for all his theories
Paracelsus, continued
Medical philosophies not popular in his own time; better known for prophecies and discussion of portents
In 1550-1575 had impact on European medicine
Attracted some royal patrons
Like Vesalius, indicative of decline of Galenic medicine
What did Vesalius and Paracelsus have in common?
Emphasis on observation vs. learning from classic texts
In Vesalius’s case, part of Early Modern return to original texts to recover truths and discover errors in translations
In Paracelsus’s case, rejection of academic medicine
Both valued empiricism though Paracelsus was much more radical in his stance
Questions You May Have:
Why do we distinguish the Middle Ages from the Early Modern Period?
What is the difference between "Early Modern" and "Renaissance"?
What should I try to remember about these figures in the history of medicine (Vesalius and Paracelsus)?